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PODCAST - Episode 6: The Role of P-gp and the Impact on Clinical Outcomes

Global DDI Solutions

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In this episode of the DDI of the Month podcast, Dr. David Burger dives into a critical topic: P-glycoprotein (P-gp)-mediated Drug-Drug Interactions with Dr. Leonie Bogaard. Join us as we explore the role of P-gp, a key transporter involved in drug absorption and elimination, and its impact on clinical outcomes.

In this episode, we discuss:

•    How P-gp modulation affects systemic drug exposure.

•    The challenges in managing DDIs due to overlap with enzymes like CYP3A4.

•    Practical recommendations for identifying and addressing P-gp-related DDIs in clinical settings.

Don’t miss this engaging discussion, featuring insights from recent research and expert recommendations on improving patient care while minimizing risks.

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This episode is available!

Website: https://academicmedicaleducation.com/ddi-month-podcast

Spotify: https://open.spotify.com/show/3Llc5rC2kKgJwenKoDvKA6

Apple: https://podcasts.apple.com/us/podcast/ddi-of-the-month-podcast/id1740543624

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Global DDI Solutions (GDDIS) was founded in 2022 by Prof. Dr. David Burger and Ms. Alice Posthumus-Plantinga to develop a suite of industry-leading drug-drug interactions (DDIs) tools and educational programs to support better quality prescribing and optimize quality of life for patients.

GDDIS aims at recording the interactions of drugs treating various diseases, and for that purpose, several DDI tools are being set up based on a central DDI database. These tools can be used to enable quick screening of DDIs.

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