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PODCAST - Episode 7: Pharmacokinetics and Green Tea: The Catechin Connection

Global DDI Solutions

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In the seventh episode, Prof. Dr. David Burger discusses with Nicki Kyriacou the review article: “Green tea catechins as perpetrators of drug pharmacokinetic interactions”.

You might think: “Green tea?– I drink it all the time! “But is it really that innocent? Tune in now as we explore how catechins – compounds found in green tea, like (-)-epigallocatechin-3-gallate – can impact drug pharmacokinetics. These compounds can alter drug solubility, transporter activity, and metabolism, potentially affecting the concentration of therapeutic drugs such as atorvastatin, digoxin, and sildenafil.

The following key topics will be discussed in the podcast:

  • The scope and intensity of green tea interaction studies
  • Different green tea formulations and their impact on drug interactions
  • Relevance for specific patient populations (especially cardiovascular medications)
  • Why green tea reduces most drug concentrations – but increases sildenafil levels
  • The role of timing in green tea consumption vs. co-medication
  • Practical guidance for clinicians and pharmacists to assess potential interaction

Don’t miss this insightful discussion on the drug interaction potential of green tea and the practical takeaways for health professionals!

Website: https://academicmedicaleducation.com/ddi-month-podcast

Spotify: https://open.spotify.com/show/3Llc5rC2kKgJwenKoDvKA6

Apple Podcast: https://podcasts.apple.com/us/podcast/ddi-of-the-month-podcast/id1740543624

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Global DDI Solutions (GDDIS) was founded in 2022 by Prof. Dr. David Burger and Ms. Alice Posthumus-Plantinga to develop a suite of industry-leading drug-drug interactions (DDIs) tools and educational programs to support better quality prescribing and optimize quality of life for patients.

GDDIS aims at recording the interactions of drugs treating various diseases, and for that purpose, several DDI tools are being set up based on a central DDI database. These tools can be used to enable quick screening of DDIs.

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